Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits histone methyltransferase activity (H3-K36 specific). Involved in several processes, including blood vessel morphogenesis; embryonic morphogenesis; and histone H3-K36 trimethylation. Localizes to chromosome and nucleus. Is expressed in 1-cell stage embryo; 2-cell stage embryo; 4-cell stage embryo; 8-cell stage embryo; and inner cell mass. Orthologous to human SETD2 (SET domain containing 2, histone lysine methyltransferase).