Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits Ras guanyl-nucleotide exchange factor activity and cAMP binding activity. Involved in cAMP-mediated signaling; regulation of vesicle-mediated transport; and secretion by cell. Localizes to cytosol and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including adrenal gland; ganglia; heart; lung; and metanephros. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human RAPGEF4 (Rap guanine nucleotide exchange factor 4).