Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable misfolded protein binding activity; signal recognition particle binding activity; and ubiquitin-specific protease binding activity. Predicted to be involved in several processes, including ERAD pathway; negative regulation of retrograde protein transport, ER to cytosol; and protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of Hrd1p ubiquitin ligase ERAD-L complex. Is expressed in several structures, including central nervous system; genitourinary system; long bone epiphyseal plate; sensory organ; and spleen. Orthologous to human DERL3 (derlin 3).