Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to enable several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; ubiquitin binding activity; and ubiquitin-protein transferase activity. Involved in isotype switching. Acts upstream of or within cellular response to UV and regulation of cellular protein localization. Part of DNA repair complex. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Used to study RIDDLE syndrome. Human ortholog(s) of this gene implicated in RIDDLE syndrome. Orthologous to human RNF168 (ring finger protein 168).