Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; ubiquitin binding activity; and ubiquitin-protein transferase activity. Involved in cellular response to UV; isotype switching; and regulation of cellular protein localization. Localizes to DNA repair complex. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Used to study RIDDLE syndrome. Human ortholog(s) of this gene implicated in RIDDLE syndrome. Orthologous to human RNF168 (ring finger protein 168).