Automated description from the Alliance of Genome Resources
Predicted to have peptidase activity, acting on L-amino acid peptides and virus receptor activity. Involved in positive regulation of cardiac muscle contraction and tryptophan transport. Localizes to the brush border membrane and cytoplasm. Used to study congestive heart failure. Human ortholog(s) of this gene implicated in diabetic retinopathy and hypertension. Is expressed in several structures, including brain; genitourinary system; heart; nasal cavity respiratory epithelium; and respiratory system. Orthologous to human ACE2 (angiotensin I converting enzyme 2).