Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables histone H2AK119 ubiquitin ligase activity. Involved in random inactivation of X chromosome. Part of PcG protein complex. Colocalizes with X chromosome. Is expressed in several structures, including branchial arch; central nervous system; limb; otocyst; and urinary system. Orthologous to human PCGF3 (polycomb group ring finger 3).