Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cyclin binding activity and protein kinase binding activity. Involved in alternative mRNA splicing, via spliceosome. Acts upstream of or within negative regulation of stem cell differentiation. Part of nuclear cyclin-dependent protein kinase holoenzyme complex. Is expressed in several structures, including future brain; genitourinary system; heart; primitive streak; and unsegmented mesenchyme. Used to study congenital heart defects, dysmorphic facial features, and intellectual developmental disorder. Human ortholog(s) of this gene implicated in congenital heart defects, dysmorphic facial features, and intellectual developmental disorder; hepatocellular carcinoma; intellectual disability; and prostate carcinoma. Orthologous to human CDK13 (cyclin dependent kinase 13).