Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to enable ubiquitin ligase-substrate adaptor activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Predicted to act upstream of or within protein ubiquitination. Predicted to be located in nuclear body and nuclear membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human KLHDC2 (kelch domain containing 2).