Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in several processes, including positive regulation of epidermal cell differentiation; regulation of epidermal cell division; and skin epidermis development. Acts upstream of or within keratinocyte development; negative regulation of keratinocyte proliferation; and negative regulation of stem cell proliferation. Located in cell cortex; cell junction; and cell leading edge. Is expressed in several structures, including alimentary system; choroid plexus; lower urinary tract; olfactory epithelium; and skin. Human ortholog(s) of this gene implicated in ectodermal dysplasia 12. Orthologous to human KDF1 (keratinocyte differentiation factor 1).