Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in several processes, including negative regulation of BMP signaling pathway; negative regulation of ossification; and negative regulation of osteoblast differentiation. Located in nuclear outer membrane. Used to study craniotubular dysplasia Ikegawa type. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Orthologous to human TMEM53 (transmembrane protein 53).