Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including cadherin binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of leukocyte migration; positive regulation of signal transduction; and vasculogenesis. Acts upstream of or within blastocyst formation; cardiac epithelial to mesenchymal transition; and nervous system development. Located in cell projection; endoplasmic reticulum membrane; and postsynaptic density. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including central nervous system; genitourinary system; limb mesenchyme; sensory organ; and skeletal musculature. Orthologous to human RTN4 (reticulon 4).