Automated description from the Alliance of Genome Resources
Exhibits insulin receptor binding activity. Involved in insulin receptor internalization; negative regulation of glucose import; and negative regulation of signal transduction. Localizes to the clathrin-coated endocytic vesicle; lysosome; and plasma membrane. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblF. Orthologous to human LMBRD1 (LMBR1 domain containing 1).