Automated description from the Alliance of Genome Resources
Exhibits endopeptidase activity. Involved in metanephros development and protein processing. Predicted to localize to the endoplasmic reticulum; gamma-secretase complex; and integral component of plasma membrane. Human ortholog(s) of this gene implicated in coronary artery disease. Is expressed in brain and genitourinary system. Orthologous to human APH1B (aph-1 homolog B, gamma-secretase subunit).