Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of hydrogen peroxide-induced cell death; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to localize to cytosol; nucleoplasm; and plasma membrane. Is expressed in genitourinary system. Used to study cleidocranial dysplasia. Orthologous to human RNF146 (ring finger protein 146).