Automated description from the Alliance of Genome Resources (Release 5.2.0)
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Predicted to be located in chromatin; mitochondrion; and nucleolus. Is expressed in several structures, including brain; limb; renal calyx; submandibular gland primordium; and tooth. Orthologous to human NACC2 (NACC family member 2).