Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 2-acylglycerol O-acyltransferase activity; diacylglycerol O-acyltransferase activity; and protein homodimerization activity. Involved in several processes, including acylglycerol biosynthetic process; cellular response to oleic acid; and cholesterol homeostasis. Located in endoplasmic reticulum; membrane; and perinuclear region of cytoplasm. Is active in endoplasmic reticulum membrane. Colocalizes with lipid droplet and mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatotic liver disease. Orthologous to human DGAT2 (diacylglycerol O-acyltransferase 2).