Automated description from the Alliance of Genome Resources (Release 5.2.2)
Enables several functions, including chromatin binding activity; histone binding activity; and p53 binding activity. Involved in negative regulation of DNA-templated transcription and negative regulation of apoptotic process. Acts upstream of or within several processes, including negative regulation of fibroblast apoptotic process; prepulse inhibition; and social behavior. Located in nucleus. Is expressed in several structures, including brain; branchial arch; genitourinary system; limb; and tail. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human CHD8 (chromodomain helicase DNA binding protein 8).