Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable nuclear estrogen receptor binding activity. Involved in axonemal dynein complex assembly; cilium movement; and determination of left/right symmetry. Acts upstream of or within several processes, including epithelial cilium movement involved in extracellular fluid movement; heart development; and learning or memory. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and spleen. Used to study Robinow syndrome and primary ciliary dyskinesia 25. Human ortholog(s) of this gene implicated in dyslexia and primary ciliary dyskinesia 25. Orthologous to human DNAAF4 (dynein axonemal assembly factor 4).