Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits protein heterodimerization activity. Contributes to cholesterol transfer activity. Involved in cholesterol homeostasis; excretion; and lipid transport. Localizes to apical plasma membrane; integral component of plasma membrane; and receptor complex. Used to study sitosterolemia. Human ortholog(s) of this gene implicated in arteriosclerosis; familial hyperlipidemia; gallbladder disease; obesity; and sitosterolemia. Orthologous to human ABCG8 (ATP binding cassette subfamily G member 8).