Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of angiogenesis; and positive regulation of intracellular signal transduction. Located in endoplasmic reticulum membrane; nucleolus; and perinuclear region of cytoplasm. Is expressed in several structures, including brain; genitourinary system; limb primordium; nose; and skin. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MTDH (metadherin).