Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ubiquitin protein ligase activity. Acts upstream of or within gamete generation and regulation of cell population proliferation. Located in nuclear envelope. Is expressed in several structures, including early embryo; gonad; heart; lung; and telencephalon ventricular layer. Used to study 46 XX gonadal dysgenesis. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group L. Orthologous to human FANCL (FA complementation group L).