Automated description from the Alliance of Genome Resources (Release 7.0.0)
A structural constituent of ribosome. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of signal transduction by p53 class mediator; and protein localization to nucleus. Located in cytoplasm and nucleolus. Part of cytosolic large ribosomal subunit. Is expressed in cerebral cortex. Used to study Diamond-Blackfan anemia 7. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Orthologous to human RPL11 (ribosomal protein L11).