Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in ERAD pathway and mannoprotein catabolic process. Acts upstream of or within glycoprotein catabolic process and proteasome-mediated ubiquitin-dependent protein catabolic process. Located in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human EDEM3 (ER degradation enhancing alpha-mannosidase like protein 3).