Automated description from the Alliance of Genome Resources
Predicted to have Ras GTPase binding activity. Involved in negative regulation of Ras protein signal transduction and protein ubiquitination. Predicted to localize to the Cul3-RING ubiquitin ligase complex; Golgi apparatus; and recycling endosome membrane. Used to study Noonan syndrome 10. Human ortholog(s) of this gene implicated in Noonan syndrome 10; Noonan syndrome 2; and neurilemmomatosis. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; eye; and urinary system. Orthologous to human LZTR1 (leucine zipper like transcription regulator 1).