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Gene Ontology Classifications
forkhead box P1

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GO curators for mouse genes have assigned the following annotations to the gene product of Foxp1. (This text reflects annotations as of Tuesday, May 26, 2015.) MGI curation of this mouse gene is considered complete, including annotations derived from the biomedical literature as of June 6, 2007. If you know of any additional information regarding this mouse gene please let us know. Please supply mouse gene symbol and a PubMed ID.
Summary text based on GO annotations supported by experimental evidence in mouse
Summary text based on GO annotations supported by experimental evidence in other organisms
Summary text based on GO annotations supported by structural data
Summary text for additional MGI annotations
  1. Hu H et al. (2006) Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol, 7:819-26. (PubMed:16819554)
  2. Jepsen K et al. (2008) Cooperative regulation in development by SMRT and FOXP1. Genes Dev, 22:740-5. (PubMed:18347093)
  3. Kelly CE et al. (2013) Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol, 11:e1001538. (PubMed:23610558)
  4. Li S et al. (2012) Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development, 139:2500-9. (PubMed:22675208)
  5. Li S et al. (2004) Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions. Mol Cell Biol, 24:809-22. (PubMed:14701752)
  6. Morikawa Y et al. (2009) Detailed expression pattern of Foxp1 and its possible roles in neurons of the spinal cord during embryogenesis. Dev Neurosci, 31:511-22. (PubMed:19797899)
  7. Palmesino E et al. (2010) Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling. PLoS Biol, 8:e1000446. (PubMed:20711475)
  8. Shu W et al. (2007) Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development, 134:1991-2000. (PubMed:17428829)
  9. Shu W et al. (2001) Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem, 276:27488-97. (PubMed:11358962)
  10. Wang B et al. (2004) Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation. Development, 131:4477-87. (PubMed:15342473)
  11. Wang H et al. (2014) The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells. Nat Immunol, 15:667-75. (PubMed:24859450)
  12. Wang Y et al. (2010) Pref-1 interacts with fibronectin to inhibit adipocyte differentiation. Mol Cell Biol, 30:3480-92. (PubMed:20457810)
  13. Zhang Y et al. (2010) Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms. Genes Dev, 24:1746-57. (PubMed:20713518)

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Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral sequence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISS Inferred from sequence or structural similarity
  ISO Inferred from sequence orthology
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  NAS Non-traceable author statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement


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