Automated description from the Alliance of Genome Resources
Exhibits chromatin binding activity and mediator complex binding activity. Involved in several processes, including embryonic viscerocranium morphogenesis; positive regulation of growth; and positive regulation of neuron migration. Localizes to the chromatin and integrator complex. Used to study Cornelia de Lange syndrome. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Orthologous to human NIPBL (NIPBL cohesin loading factor).