Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including Rho GTPase binding activity; beta-catenin destruction complex binding activity; and identical protein binding activity. Involved in several processes, including protein localization to organelle; regulation of cellular protein metabolic process; and regulation of signal transduction. Localizes to several cellular components, including Wnt signalosome; cytoplasmic vesicle; and mitochondrion. Is expressed in several structures, including gut; immune system; liver; lung; and musculature. Used to study Parkinson's disease 8. Human ortholog(s) of this gene implicated in Crohn's disease; Parkinson's disease; Parkinson's disease 8; and cancer. Orthologous to human LRRK2 (leucine rich repeat kinase 2).