Automated description from the Alliance of Genome Resources
Exhibits several functions, including Rho GTPase binding activity; beta-catenin destruction complex binding activity; and identical protein binding activity. Involved in several processes, including positive regulation of cellular metabolic process; protein localization to organelle; and regulation of signal transduction. Localizes to several cellular components, including the Wnt signalosome; cytoplasm; and glutamatergic synapse. Used to study autosomal dominant Parkinson's disease 8. Human ortholog(s) of this gene implicated in Crohn's disease; Parkinson's disease; autosomal dominant Parkinson's disease 8; and cancer. Orthologous to human LRRK2 (leucine rich repeat kinase 2).