Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have microtubule binding activity; rRNA binding activity; and ribosome binding activity. Involved in inner cell mass cell proliferation. Predicted to localize to cytosol; nuclear lumen; and spindle pole. Used to study Shwachman-Diamond syndrome. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome; aplastic anemia; exocrine pancreatic insufficiency; and hematopoietic system disease. Is expressed in several structures, including gonad; gut; immune system; liver; and lung. Orthologous to human SBDS (SBDS ribosome maturation factor).