Automated description from the Alliance of Genome Resources (Release 4.0)
Enables leucine-tRNA ligase activity. Involved in leucyl-tRNA aminoacylation. Part of aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in infantile liver failure syndrome 1. Orthologous to human LARS1 (leucyl-tRNA synthetase 1).