Automated description from the Alliance of Genome Resources (Release 5.1.1)
Enables water channel activity. Involved in several processes, including cellular water homeostasis; negative regulation of ERAD pathway; and oxygen homeostasis. Acts upstream of or within endosomal lumen acidification; proximal tubule development; and water transport. Located in endoplasmic reticulum; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and immune system. Orthologous to human AQP11 (aquaporin 11).