Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables endoplasmic reticulum-autophagosome adaptor activity. Involved in negative regulation of neuron apoptotic process. Acts upstream of or within several processes, including collagen catabolic process; macroautophagy; and white fat cell differentiation. Located in cis-Golgi network and endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; ganglia; metanephros; and reproductive system. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 2B. Orthologous to human RETREG1 (reticulophagy regulator 1).