Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables SUMO transferase activity. Acts upstream of or within several processes, including negative regulation of macromolecule biosynthetic process; negative regulation of osteoclast differentiation; and protein sumoylation. Located in cytoplasm and nucleus. Is expressed in several structures, including blastocyst; central nervous system; eye; genitourinary system; and maxillary process. Orthologous to human PIAS3 (protein inhibitor of activated STAT 3).