Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have RNA polymerase II repressing transcription factor binding activity. Involved in several processes, including brain development; regulation of actin filament organization; and regulation of blood vessel diameter. Localizes to kinociliary basal body and motile cilium. Is expressed in embryo and urogenital ridge. Used to study Bardet-Biedl syndrome 6 and obesity. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 6; McKusick-Kaufman syndrome; congenital heart disease; and obesity. Orthologous to human MKKS (McKusick-Kaufman syndrome).