Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits AP-2 adaptor complex binding activity and calcium ion binding activity. Involved in synaptic vesicle priming. Localizes to endoplasmic reticulum; presynaptic active zone membrane; and synaptic vesicle membrane. Is expressed in brain; pons mantle layer; and rest of cerebellum ventricular layer. Used to study autosomal recessive nonsyndromic deafness 9. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 9. Orthologous to human OTOF (otoferlin).