Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits [methionine synthase] reductase activity. Involved in several processes, including S-adenosylmethionine cycle; folic acid metabolic process; and sulfur amino acid metabolic process. Predicted to localize to cytosol. Is expressed in several structures, including gut; neural ectoderm; notochord; optic vesicle; and placenta. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); heart disease (multiple); hematologic cancer (multiple); homocystinuria; and ulcerative colitis. Orthologous to human MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase).