Automated description from the Alliance of Genome Resources (Release 7.0.0)
Acts upstream of or within regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Orthologous to human BRWD1 (bromodomain and WD repeat domain containing 1).