Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ATP binding activity; metal ion binding activity; and protein serine/threonine kinase activity. Acts upstream of or within determination of left/right symmetry and heart development. Located in ciliary base and ciliary inversin compartment. Is expressed in collecting duct; cortical renal tubule; node; and renal tubule. Used to study autosomal recessive polycystic kidney disease. Human ortholog(s) of this gene implicated in nephronophthisis 9 and renal-hepatic-pancreatic dysplasia. Orthologous to human NEK8 (NIMA related kinase 8).