Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; protein phosphatase 2A binding activity; and sequence-specific DNA binding activity. Involved in several processes, including cellular response to nitric oxide; neuronal stem cell population maintenance; and positive regulation of cellular biosynthetic process. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; early conceptus; and sensory organ. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to human FOXO1 (forkhead box O1).