Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables serotonin-gated monoatomic cation channel activity. Predicted to be involved in several processes, including chemical synaptic transmission; inorganic cation transmembrane transport; and monoatomic ion transmembrane transport. Predicted to act upstream of or within monoatomic cation transmembrane transport and serotonin receptor signaling pathway. Located in plasma membrane. Is expressed in several structures, including adrenal gland; aorta-gonad-mesonephros; genitourinary system; gut; and nervous system. Human ortholog(s) of this gene implicated in alcohol use disorder and depressive disorder. Orthologous to human HTR3B (5-hydroxytryptamine receptor 3B).