Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable RNA binding activity; pseudouridine synthase activity; and telomerase activity. Acts upstream of or within box H/ACA RNA metabolic process; positive regulation of telomere maintenance via telomerase; and rRNA pseudouridine synthesis. Located in Cajal body and nucleolus. Is expressed in several structures, including brain; epithelium; genitourinary system; skin; and surface ectoderm. Used to study dyskeratosis congenita. Human ortholog(s) of this gene implicated in X-linked dyskeratosis congenita; aplastic anemia; and dyskeratosis congenita. Orthologous to human DKC1 (dyskerin pseudouridine synthase 1).