Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable SH3 domain binding activity and actin filament binding activity. Involved in negative regulation of cytoskeleton organization. Acts upstream of or within locomotory behavior; parallel actin filament bundle assembly; and positive regulation of filopodium assembly. Located in actin cytoskeleton; brush border; and stereocilium. Is active in stereocilium tip. Is expressed in organ of Corti; ovary; seminiferous tubule; seminiferous tubule epithelium; and testis. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 36. Orthologous to human ESPN (espin).