Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity and phosphatidylinositol-3,5-bisphosphate binding activity. Predicted to be involved in several processes, including Golgi disassembly; Golgi vesicle transport; and protein localization to organelle. Predicted to be located in several cellular components, including Golgi apparatus; endoplasmic reticulum lumen; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in brain; embryo; and head. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate A. Orthologous to human GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1).