Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables guanyl-nucleotide exchange factor activity and protein kinase binding activity. Involved in lamellipodium assembly. Acts upstream of or within several processes, including hematopoietic progenitor cell differentiation; positive regulation of GTPase activity; and positive regulation of growth hormone secretion. Located in several cellular components, including lamellipodium; postsynapse; and storage vacuole. Is expressed in several structures, including metanephros; nervous system; and retina. Orthologous to human ARHGEF7 (Rho guanine nucleotide exchange factor 7).