Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable wide pore channel activity. Predicted to be involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Predicted to be located in cytoplasmic vesicle. Predicted to be active in phagolysosome membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; liver; lung; and spleen. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MPEG1 (macrophage expressed 1).