Automated description from the Alliance of Genome Resources
Predicted to have actin binding activity and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of NLRP3 inflammasome complex assembly; negative regulation of cytokine production; and positive regulation of cellular metabolic process. Predicted to localize to the cytosol; microtubule associated complex; and nucleoplasm. Used to study familial Mediterranean fever. Human ortholog(s) of this gene implicated in Henoch-Schoenlein purpura; asthma; familial Mediterranean fever; hematologic cancer (multiple); and lung disease. Is expressed in bladder; female associated reproductive structure; ureter; and urethra of female. Orthologous to human MEFV (MEFV innate immuity regulator, pyrin).