Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables Toll-like receptor binding activity. Involved in endolysosomal toll-like receptor signaling pathway and intracellular protein transport. Acts upstream of or within several processes, including T cell antigen processing and presentation; antigen processing and presentation of exogenous peptide antigen via MHC class II; and positive regulation of cytokine production. Located in cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Is expressed in brain; cerebral cortex; liver; lung; and spleen. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human UNC93B1 (unc-93 homolog B1, TLR signaling regulator).