Automated description from the Alliance of Genome Resources
Predicted to have cytoskeletal protein binding activity and microtubule-severing ATPase activity. Involved in anterograde axonal transport; axonal transport of mitochondrion; and microtubule severing. Localizes to the microtubule cytoskeleton and nucleus. Predicted to colocalize with the endoplasmic reticulum and endosome. Used to study hereditary spastic paraplegia 4. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 4. Orthologous to human SPAST (spastin).