Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits protein homodimerization activity; signaling receptor binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including ion homeostasis; positive regulation of PERK-mediated unfolded protein response; and regulation of programmed cell death. Localizes to bounding membrane of organelle; endoplasmic reticulum membrane; and mitochondrial membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; gut; retina; and vibrissa dermal component. Orthologous to human BOK (BCL2 family apoptosis regulator BOK).