Automated description from the Alliance of Genome Resources
Predicted to have interleukin-1 receptor binding activity. Predicted to be involved in positive regulation of interleukin-8 production; positive regulation of nitric oxide biosynthetic process; and positive regulation of toll-like receptor signaling pathway. Predicted to localize to the membrane. Human ortholog(s) of this gene implicated in Legionnaires' disease; cystic fibrosis; cystitis; melioidosis; and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5).