Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable co-receptor binding activity and receptor antagonist activity. Predicted to be involved in negative regulation of DNA-templated transcription; negative regulation of canonical Wnt signaling pathway; and negative regulation of steroid hormone biosynthetic process. Predicted to act upstream of or within Wnt signaling pathway. Located in extracellular space. Is expressed in several structures, including brain; cardiovascular system; limb; sensory organ; and tooth. Orthologous to human DKK3 (dickkopf WNT signaling pathway inhibitor 3).